Hi, it must be so frustrating for you to be going through this whilst supporting your husband at the same time. Such trying times for you both. I have a recent diagnosis of rectal cancer metastasis to liver and have had x2 chemo sessions with the 3rd this coming Wednesday. After my 1st session I had some strange side effects with what I can only explain as anxiety/jitters to give you the short version, which I mentioned to my oncologist. She suggested these were due to the steroids I have as part of my chemo and adjusted the dosage which significantly reduced the side effects. She also prescribed me Lorazepam.  I am not saying this is the 'fix' for your husband and I am obviously unsure if he has steroids as a part of his treatment but I have read that they can cause mood changes. I understand you may not want to bring what happened up to your husband but it may help if you somehow can and then together inform one of his doctors or nurses who may be able to pinpoint the cause, especially since it is out of character. Good Luck loving wife and wishing the best possible outcome for your husband. ... View more