I have a sister who's in her 30s, and has been bleeding steadily/daily for over 2 years and no one seemed to know why. She said there were a few days where there was nothing or light spotting but otherwise she's been on an endless cycle. We finally convinced her to go to a doctor, who tested her hormones (high cortisol, normal estrogen and thyroid, very low progesterone) and sent her for a vaginal ultrasound. Came back clear, no cysts, no polyps, but with a lining of 16mm. Biopsy was done, normal but had bacterial vaginosis. Told her to lose weight and get in birth control. Now, she's bleeding more it seems, always clotting, says she's up til 3am some nights just bleeding. Doesn't go out for fear of bleeding through her clothes. Went in again, ultrasound was still at 16mm (16 months between ultrasounds), but this time they said "The endometrium is heterogeneous in echotexture, There are no uterine myometrial masses, Abnormally thickened heterogeneous endometrium." They want to do another biopsy, worried it's turned into cancer, but she doesn't want to do it, says it's probably just a weight thing and poor diet, and said since there are no masses or cysts, it can't be cancer. Our mom is a breast cancer survivor, grandpa had several types of cancer, lots of weird autoimmune stuff runs in the family. I don't know what to do, how do I convince her to at least try and rule it out or get a second opinion? I don't know what the heterogeneous echo texture stuff means but I'm so worried about her, any help or advice is deeply appreciated! ... View more