Thought I would set up this thread of discussion as I know the forums are set up for individual Diagnosis types however I believe that there are many Advanced Breast cancer sufferers and carers who would like to share their ideas, questions, fears and support to the wider group. I am a carer and my wife has had advanced breast cancer now for just over 2 years after it was picked up in the chest and the liver. She is ER+PR+ Her2neu and for the first 12 months was on hormonal treatment (letrozole). When this failed she has been on xeloda and Avastin for 14 months with a partial response (in other words medically the growths have reduced by more than 30%). The biggest issue I have as a carer is getting the right information to ensure the best result for my wife and quality of life. I believe the best way is through forums like this where you can share your experiences and support each other.