Hi, From the discussions I've had with other cancer patients, everybody reacts a little bit differently to chemo, even to the same chemotherapy drugs. Personally, I didn't experience a great deal of tiredness/exhaustion until round 9. For the first 4 or 5 rounds, I would just go back to my work office and continue working. After each round the side effects were just a little worse, but after round 9 of FOLFOX, the fatigue hit me like a brick. I would just go home and sleep for the rest of the day. I couldn't manage anything else. But everyone is different. How is your brother going now? Has he finished treatment? Hope all is well -s
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